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Chromium: A Tool to Fight Syndrome-X!
Bill Bailey, Ph.D., MH, ND, CNHP, CTN
(Dr. Bailey can be reached at Traditional Naturopath) |
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Chromium has
been studied in the past primarily for improving blood sugar control in
people with diabetes, but recent evidence suggests that Chromium may
also help reduce body fat, probably through its effects on insulin.
1,2,3 As we know from previous articles, insulin is the "fat
storing hormone." Chromium's effect on insulin sensitivity appears to
be marked. It reduces your body's "conversion" of carbohydrates to body
fat through the phenomenon some clinicians have termed "Syndrome-X."
The American Heart Association, on their web site, defines "Syndrome-X"
in this way: "Syndrome-X has been observed in people who are
insulin-resistant. One such group is people with diabetes , who have a
defect in insulin action and can't maintain a proper level of glucose in
their blood. Another is people, mainly hypertensives (those with high
blood pressure), who are non-diabetic and insulin-resistant but who
compensate by secreting large amounts of insulin. This condition is
known as hyperinsulinemia. A third group is heart attack survivors who,
unlike people with hypertension, have hyperinsulinemia without having
abnormal glucose levels." In their book, Syndrome-X, the authors say
that "...insulin resistance and Syndrome X are caused primarily by
a diet high in refined carbohydrates, which probably include
many of your favorite and frequently eaten foods, such as cereals,
muffins, breads and rolls, pastas, cookies, donuts, and soft drinks.
These refined carbohydrates not only raise glucose and insulin to
unhealthy levels, but they also are devoid of the many vitamins,
minerals, and vitamin-like nutrients our bodies need to properly utilize
these foods." (Syndrome-X, Introduction, January 2000, Jack Challem,
Burt Berkson, M.D., Ph.D. Melissa Diane Smith. Emphasis mine.)
Supplementing
Chromium has exactly the effect we want... it reduces insulin
sensitivity and thus prevents build-up of body fat. This will lead to
an overall improvement of fat-to-lean body composition. Body
composition is determined by the ratio of fat-free mass versus the
amount of fatty tissue in the body. In "layman's terms" this would be
the percentage of body fat to lean muscle mass. This effect of
improving body composition by supplementation of Chromium is
demonstrated in a 1998 study, "The data clearly confirm that
supplementation with Chromium picolinate (one form of chromium) can lead
to significant improvements in body composition resulting from fat loss,
particularly for individuals who may not be as aggressive in making
lifestyle changes such as reducing caloric intake or increasing their
physical activity," says Gilbert Kaats, Ph.D., of the Health and Medical
Research Foundation in San Antonio, the lead investigator in the
multi-authored study, which was reported in the June 1998 issue of
Current Therapeutic Research.
Subjects
involved in the study were provided 400 micrograms of Chromium or a
placebo daily. Changes in body fat, fat-free mass, and weight were
measured over a 90-day period. The study lasted 3-months and was a
double-blind study of 122 moderately overweight people and found that
400 mcg of Chromium daily resulted in an average loss of 6.2 pounds of
body fat, as opposed to 3.4 pounds in the placebo group. The results of
the study demonstrated a statistically significant reduction in body fat
(and fat mass) in those individuals who took Chromium, without losing
any valuable lean body mass. These results suggest that Chromium can
help you lose fat without losing muscle.
The authors
noted, "It has been proposed that Chromium picolinate's positive effect
on body composition is through its ability to improve insulin
utilization, thereby reducing fat deposition and resulting in improving
entry of glucose and amino acids into muscle cells. Although this study
did not attempt to test this assertion, the findings are consistent with
this hypothesis."1
This benefit to
the dieter's goal of weight loss by correcting the effects of insulin on
fat storage is further substantiated by an article in Medical
Hypotheses: "Increased pancreatic beta-cell secretory activity
usually is associated with decreased alpha-cell activity; stimulated
beta-cells release gamma-aminobutyric acid, which hyperpolarizes
alpha-cells, inhibiting glucagon release. Thus, insulin secretion and
glucagon secretion are usually inversely coupled. This suggests that
Chromium and other insulin-sensitizing modalities, by down-regulating
beta-cell activity, may increase glucagon secretion. Such an effect
might play a role in the documented therapeutic activity of supplemental
Chromium and biguanides in reactive hypoglycemia, and might also be of
benefit to dieters." 4
So, we have
seen that Chromium supplementation has been shown to preserve muscle
while accelerating the loss of adipose tissue (body fat.) It is an
effective deterrent to "Syndrome-X" effects. All forms of trivalent
Chromium are effective. ChromeMate® Brand of Chromium has been shown to
be the most bio-available form of Chromium in recent studies!
Chromium also
seems to have significant cholesterol-lowering abilities, according to
new research. Researchers combined data from five previous
double-blind, placebo controlled studies involving more than 300
patients. Total blood cholesterol levels fell more than 20 points on
average, going from more than 220 mg/dl to less than 200 mg/dl, in
subjects receiving Chromium. Study participants were not on any lipid
lowering medications. Supplementation with 1,000 mcg had the greatest
effect, although doses as low as 200 mcg also significantly lowered
blood cholesterol.5 Doses of higher than 400mcg daily are
not recommended by most clinicians, however. To further substantiate
Chromium's benefit to cholesterol reduction; we see in a very recent
study that there are indications that Chromium may also be important for
blood cholesterol reduction and a lessening of the risk of diabetes and
heart disease. The not-for-profit educational organization, the
Chromium Information Bureau reports that Dr. Danielle Greenberg,
nutritional scientist at Purchase, NY-based AMBI, Inc., presented
research linking Chromium and cholesterol at a meeting of the American
College of Nutrition. On average, total blood cholesterol fell more
than 20 points in people receiving Chromium picolinate.6
So we see that Chromium can be a valuable tool in our dietary arsenal
against weight gain, as well as other documented health benefits! Many
researchers have recommended Chromium supplementation as an aid in one's
weight loss program. The highest naturally occurring source for
Chromium in herbal form is Stevia... for more Stevia info click
HERE!
Boston
University's HealthSource web site summarizes Chromium's benefits with
these points:
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Works with insulin in the
metabolism of sugar and stabilizes blood sugar levels
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cleans the arteries by
reducing Cholesterol & Triglyceride levels
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helps transport amino
acids to where the body needs them
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helps control the appetite
-
medical research has shown
that persons with low levels of Chromium in their bodies are more
susceptible to having cancer and heart problems and becoming diabetic
Low Carb
Nexus® Chromium is the highest quality of
bioactive Chromium available... it is available
HERE!
-
Kaats GR, Blum K, Pullin D, et al. A
randomized, double-masked, placebo-controlled study of the effects of
chromium picolinate supplementation on body composition: a replication
and extension of a previous study. Current Therapeutic Research.
June 1998;59:379 388.
-
Hoeger WWK, Harris C, Long EM, et al. Four-week supplementation with a
natural dietary compound produces favorable changes in body
composition. Adv Ther. 1998;15:305 314.
- Grant KE,
Chandler RM, Castle AL, et al. Chromium and exercise training: effect
on obese women. Med Sci Sports Exerc. 1997;29:992 998.
- Medical
Hypotheses, February 1996, 46(2):77-80
- Journal of
the American College of Nutrition November, 2000; 19: 687
-
Whole Foods Magazine, January
2001, Newslinks, 22
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